I’d urge you to organize your workplace and form a union. You can contact organizers at the AFL-CIO (a kind of union of unions in the US) and find which union is right for your workplace. If you don’t work but are still able to do physical or intellectual labor, start getting as involved in your local community as possible… volunteer at food banks, after school programs, nursing homes, etc. The more people you can reach out to and help or with whom you can organize the better. If you cannot do those things due to personal issues (disability, etc), do what you can in encouraging others to take these steps. You have a voice here on the internet (at the very least), educate yourself as best as you can on how folks can help one another and encourage others to take these steps.
A massive action like a general strike isn’t just organized over night by total strangers… it takes communities with common cause and familiarity with one another. Realistically, if anyone is calling a general strike, odds are it’ll be like the United Auto Workers kicking shit off. Maybe the railroad folks or the International Brotherhood of Electrical Workers, but more than likely the UAW will lead the charge.
You’re on the right track asking “how to” and that’s great! Organizing is a rough road, but it’s vital and worth it… the more people doing it the better in any capacity. United we bargain, divided we beg.
If the USA were to have a general strike, it’s more than likely that the UAW would be the ones calling for it. They’re a very large union of which most Americans are aware and likely have a very high approval amongst average people.