It gets worse over time but it also eventually gets better, after the deleterious recessive alleles have been eliminated. Like in herd animals where a herd has only one breeding male per generation, so every generation is half-siblings.
The general rule is that a population with a fixed degree of inbreeding will have a corresponding number of deleterious alleles so that the selection pressure balances out; but when you change the degree of inbreeding, you get a spike in expressed mutations until things balance out again.
Not necessarily. If the problem is on a recessive gene or it isn’t a problem with only one out of two genes expressing the trait, the genetic disease won’t get bred out of the family.
It gets worse over time but it also eventually gets better, after the deleterious recessive alleles have been eliminated. Like in herd animals where a herd has only one breeding male per generation, so every generation is half-siblings.
The general rule is that a population with a fixed degree of inbreeding will have a corresponding number of deleterious alleles so that the selection pressure balances out; but when you change the degree of inbreeding, you get a spike in expressed mutations until things balance out again.
Which family line discovered this one? :)
Not necessarily. If the problem is on a recessive gene or it isn’t a problem with only one out of two genes expressing the trait, the genetic disease won’t get bred out of the family.